Glass Crystallization Reactor in pharmaceutical industry

2025-12-28

Glass crystallization reactor is a key equipment used in the pharmaceutical industry for drug crystallization, purification, small-scale and pilot production. 

Glass Crystallization Reactor has the characteristics of high chemical stability, transparency and visibility, and multifunctional integration (such as stirring, filtration, distillation), and is widely used in raw material synthesis, peptide preparation, and scientific research experiments.
In the pharmaceutical industry, the Glass Crystallization Reactor crystallization process is one of the core steps for separating and purifying active pharmaceutical ingredients (APIs).

 The glass crystallization reactor is an ideal choice for laboratory research and small-scale production due to its use of high borosilicate glass (such as GG-17/Borosilicate 3.3), which has excellent corrosion resistance, thermal stability, and reaction process visualization advantages. It is commonly used in processes such as drug molecule eutectic synthesis, solvent recovery, and vacuum filtration.
These Glass Crystallization Reactor are usually equipped with jacket structures that can be connected to heating/cooling circulation systems, supporting reactions under high temperature, low temperature, or vacuum conditions, and meeting the sensitive temperature and pressure requirements of different drug systems
Function and application scenarios of Glass Crystallization Reactor 
Drug crystallization and recrystallization: achieving high-purity crystal precipitation, improving drug stability and bioavailability.
Peptide and biologics synthesis: suitable for biochemical reactions sensitive to metal ions, avoiding contamination.
Teaching and pilot scale: Transparent design facilitates observation of crystal growth process, supporting the transition from small-scale trials to industrialization.
Continuous operation integration: Combined with vacuum filtration and bottom discharge valve (PTFE material), the reaction → filtration → collection can be completed in the same reactor, reducing material transfer losses
glass lined reactor in pharmaceutical industry

50L Factory Price chemical Jacketed Glass Crystallization Reactor

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